To City Nights from the South Bay: - Take 101 north to the 80 East San Francisco Bay Bridge Take the last San Francisco exit on your rt side, which is 4th street At the light, go slightly to the left to merge with Bryant st Make a left on 3rd street And a left on Harrison X and City Nights is located at 715 Harrison St immediately on your left side inbetween Third and Fourth street. To City Nights from the East Bay: Take the 580 or 880 freeways to the 80 West San Francisco Bay Bridge - On your right side, take the Fremont street exit Stay on your right side and as the exit splits, take the right towards Folsom street - Go straight at the light and make a right onto Harrison street X and City Nights is located at 715 Harrison on your left side inbetween Third and Fourth street.